Microjaponin, A New Dihydroagarofuranoid Sesquiterpene from the Stem ofMicrotropis japonicawith Antituberculosis Activity

Autor:	Ih-Sheng Chen, Yun-Ping Lim, Chien Fang Peng, Wen Lung Kuo, Ming Jen Cheng, Jih Jung Chen, Ping-Jyun Sung
Rok vydání:	2014
Předmět:	Spectrometry Mass Electrospray Ionization Magnetic Resonance Spectroscopy Stereochemistry Antitubercular Agents Bioengineering Microbial Sensitivity Tests Sesquiterpene Benzoates Biochemistry Mycobacterium tuberculosis chemistry.chemical_compound Sesquiterpenes Eudesmane Molecular Biology Molecular Structure Plant Stems biology Chemistry General Chemistry General Medicine Celastraceae biology.organism_classification Microjaponin Microtropis japonica Molecular Medicine Sesquiterpenes
Zdroj:	Chemistry & Biodiversity. 11:1241-1246
ISSN:	1612-1872
Popis:	A new dihydroagarofuran-based sesquiterpene, microjaponin (1), was isolated from the stem of Microtropis japonica. Its structure was determined by in-depth spectroscopic and mass-spectrometric analyses. Microjaponin (1) exhibited potent in vitro antituberculosis activity, with an MIC value of 12.5 μg/ml against Mycobacterium tuberculosis H37 Rv.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4be3cd777a36125059dd7b13f7af80b https://doi.org/10.1002/cbdv.201400066 Zobrazit plný text záznamu Plný text