L-cysteine modified ZnO: Small change while great progress
| Autor: | Wenying Xu, Lan Liao, Ziyu Zhou, Jiaolong Wang, Feng Zhang, Runfa Wu, Junchao Wei, Xianhua Zhang, Wang Xiaolei |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Indoles Materials science Biocompatibility Cell Survival Polymers Administration Oral Metal Nanoparticles Bioengineering Nanotechnology 02 engineering and technology 010402 general chemistry 01 natural sciences Nanomaterials Biomaterials Mice Spectroscopy Fourier Transform Infrared Animals Cysteine Lung Photoelectron Spectroscopy 021001 nanoscience & nanotechnology Anti-Bacterial Agents 0104 chemical sciences Liver Mechanics of Materials Thermogravimetry NIH 3T3 Cells Surface modification Zinc Oxide 0210 nano-technology |
| Zdroj: | Materials Science and Engineering: C. 103:109818 |
| ISSN: | 0928-4931 |
| DOI: | 10.1016/j.msec.2019.109818 |
| Popis: | ZnO as an important nanomaterial have been widely used in biomedical fields, however, ZnO has noticeable damage to the organs such as lung and liver, from the long run, its biosafety still needs improvements. In this work, we proposed a simple method to modify the surface of ZnO with l-cysteine. The basic characterizations showed that the surface modification can greatly affect its self-assembly and optical properties. Furthermore, the surface modification can greatly improve its biocompatibility and without change of its bulk antibacterial properties. Moreover, compared with ZnO, the l-cysteine modified ZnO showed much better biosafety in the in vivo test, demonstrating that the modified ZnO may have perspective applications in biomedical fields. |
| Databáze: | OpenAIRE |
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