| Autor: |
Gupta, Shruti, Hayek, Salim S., Wang, Wei, Chan, Lili, Mathews, Kusum S., Melamed, Michal L., Brenner, Samantha K., Leonberg-Yoo, Amanda, Schenck, Edward J., Radbel, Jared, Reiser, Jochen, Bansal, Anip, Srivastava, Anand, Zhou, Yan, Sutherland, Anne, Green, Adam, Shehata, Alexandre M., Goyal, Nitender, Vijayan, Anitha, Velez, Juan Carlos Q., Shaefi, Shahzad, Parikh, Chirag R., Arunthamakun, Justin, Athavale, Ambarish M., Friedman, Allon N., Short, Samuel A. P., Kibbelaar, Zoe A., Abu Omar, Samah, Admon, Andrew J., Donnelly, John P., Gershengorn, Hayley B., Hernán, Miguel A., Semler, Matthew W., Leaf, David E., Walther, Carl P, Anumudu, Samaya J, Kopecky, Kathleen F, Milligan, Gregory P, McCullough, Peter A, Nguyen, Thuy-Duyen, Krajewski, Megan L, Shankar, Sidharth, Pannu, Ameeka, Valencia, Juan D, Waikar, Sushrut S, Hart, Peter, Ajiboye, Oyintayo, Itteera, Matthew, Rachoin, Jean-Sebastien, Schorr, Christa A, Shea, Lisa, Edmonston, Daniel L, Mosher, Christopher L, Karp, Aaron, Cohen, Zaza, Allusson, Valerie, Bambrick-Santoyo, Gabriela, Bhatti, Noor ul aain, Mehta, Bijal, Williams, Aquino, Walters, Patricia, Go, Rolando C, Rose, Keith M, Zhou, Amy M, Kim, Ethan C, Lisk, Rebecca, Coca, Steven G, Altman, Deena R, Saha, Aparna, Soh, Howard, Wen, Huei Hsun, Bose, Sonali, Leven, Emily A, Wang, Jing G, Mosoyan, Gohar, Nadkarni, Girish N, Guirguis, John, Kapoor, Rajat, Meshberger, Christopher, Garibaldi, Brian T, Corona-Villalobos, Celia P, Wen, Yumeng, Menez, Steven, Malik, Rubab F, Cervantes, Carmen Elena, Gautam, Samir C, Nguyen, H Byrant, Ahoubim, Afshin, Thomas, Leslie F, Sirganagari, Dheeraj Reddy, Guru, Pramod K, Bergl, Paul A, Rodriguez, Jesus, Shah, Jatan A, Gupta, Mrigank S, Kumar, Princy N, Lazarous, Deepa G, Kassaye, Seble G, Johns, Tanya S, Mocerino, Ryan, Prudhvi, Kalyan, Zhu, Denzel, Levy, Rebecca V, Azzi, Yorg, Fisher, Molly, Yunes, Milagros, Sedaliu, Kaltrina, Golestaneh, Ladan, Brogan, Maureen, Raichoudhury, Ritesh, Cho, Soo Jung, Plataki, Maria, Alvarez-Mulett, Sergio L, Gomez-Escobar, Luis G, Pan, Di, Lee, Stefi, Kirshnan, Jamuna, Whalen, William, Charytan, David, Macina, Ashley, Ross, Daniel W, Leidner, Alexander S, Martinez, Carlos, Kruser, Jacqueline M, Wunderink, Richard G, Hodakowski, Alexander J, Price-Haywood, Eboni G, Matute-Trochez, Luis A, Hasty, Anne E, Mohamed, Muner MB, Avasare, Rupali S, Zonies, David, Baron, Rebecca M, Sise, Meghan E, Newman, Erik T, Pokharel, Kapil K, Sharma, Shreyak, Singh, Harkarandeep, Correa, Simon, Shaukat, Tanveer, Kamal, Omer, Yang, Heather, Boateng, Jeffery O, Lee, Meghan, Strohbehn, Ian A, Li, Jiahua, Muhsin, Saif A, Mandel, Ernest I, Mueller, Ariel L, Cairl, Nicholas S, Rowan, Chris, Madhai-Lovely, Farah, Peev, Vasil, Byun, John J, Vissing, Andrew, Kapania, Esha M, Post, Zoe, Patel, Nilam P, Hermes, Joy-Marie, Patrawalla, Amee, Finkel, Diana G, Danek, Barbara A, Arikapudi, Sowminya, Paer, Jeffery M, Puri, Sonika, Sunderram, Jag, Scharf, Matthew T, Ahmed, Ayesha, Berim, Ilya, Hussain, Sabiha, Anand, Shuchi, Levitt, Joseph E, Garcia, Pablo, Boyle, Suzanne M, Song, Rui, Zhang, Jingjing, Sharshir, Mohd A, Rusnak, Vadym V, Podoll, Amber S, Chonchol, Michel, Sharma, Sunita, Burnham, Ellen L, Rashidi, Arash, Hejal, Rana, Judd, Erik T, Latta, Laura, Tolwani, Ashita, Albertson, Timothy E, Adams, Jason Y, Chang, Steven Y, Beutler, Rebecca M, Schulze, Carl E, Macedo, Etienne, Rhee, Harin, Liu, Kathleen D, Jotwani, Vasantha K, Koyner, Jay L, Shah, Chintan V, Jaikaransingh, Vishal, Toth-Manikowski, Stephanie M, Joo, Min J, Lash, James P, Neyra, Javier A, Chaaban, Nourhan, Iardino, Alfredo, Au, Elizabeth H, Sharma, Jill H, Sosa, Marie Anne, Taldone, Sabrina, Contreras, Gabriel, Zerda, David De La, Blakely, Pennelope, Berlin, Hanna, Azam, Tariq U, Shadid, Husam, Pan, Michael, OHayer, Patrick, Meloche, Chelsea, Feroze, Rafey, Padalia, Kishan J, Bitar, Abbas, Flythe, Jennifer E, Tugman, Matthew J, Brown, Brent R, Spiardi, Ryan C, Miano, Todd A, Roche, Meaghan S, Vasquez, Charles R, Bansal, Amar D, Ernecoff, Natalie C, Kovesdy, Csaba P, Molnar, Miklos Z, Azhar, Ambreen, Hedayati, Susan S, Nadamuni, Mridula V, Khan, Sadaf S, Willett, Duwayne L, Renaghan, Amanda D, Bhatraju, Pavan K, Malik, Bilal A, Joy, Christina Mariyam, Li, Tingting, Goldberg, Seth, Kao, Patricia F, Schumaker, Greg L, Faugno, Anthony J, Hsu, Caroline M, Tariq, Asma, Meyer, Leah, Weiner, Daniel E, Christov, Marta, Wilson, Francis P, Arora, Tanima, Ugwuowo, Ugochukwu |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
JAMA Internal Medicine |
| ISSN: |
2168-6106 |
| Popis: |
Importance: The US is currently an epicenter of the coronavirus disease 2019 (COVID-19) pandemic, yet few national data are available on patient characteristics, treatment, and outcomes of critical illness from COVID-19. Objectives: To assess factors associated with death and to examine interhospital variation in treatment and outcomes for patients with COVID-19. Design, Setting, and Participants: This multicenter cohort study assessed 2215 adults with laboratory-confirmed COVID-19 who were admitted to intensive care units (ICUs) at 65 hospitals across the US from March 4 to April 4, 2020. Exposures: Patient-level data, including demographics, comorbidities, and organ dysfunction, and hospital characteristics, including number of ICU beds. Main Outcomes and Measures: The primary outcome was 28-day in-hospital mortality. Multilevel logistic regression was used to evaluate factors associated with death and to examine interhospital variation in treatment and outcomes. Results: A total of 2215 patients (mean [SD] age, 60.5 [14.5] years; 1436 [64.8%] male; 1738 [78.5%] with at least 1 chronic comorbidity) were included in the study. At 28 days after ICU admission, 784 patients (35.4%) had died, 824 (37.2%) were discharged, and 607 (27.4%) remained hospitalized. At the end of study follow-up (median, 16 days; interquartile range, 8-28 days), 875 patients (39.5%) had died, 1203 (54.3%) were discharged, and 137 (6.2%) remained hospitalized. Factors independently associated with death included older age (≥80 vs |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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