Case Series of Severe Neurologic Sequelae of Ebola Virus Disease during Epidemic, Sierra Leone

Autor: Anna R. Walder, Abdul N’jai, Jonathon M. Read, Reena Dwivedi, Tom Solomon, Janet T Scott, Patrick Howlett, Nicholas A. V. Beare, Marta Lado, Gibrilla F. Deen, F. R. Sesay, Foday Sahr, Colin S Brown, Malcolm G Semple, Durodami Radcliffe Lisk, Stephen Sevalie, Paul J. Steptoe, Marylou Solbrig, Felicity Fitzgerald
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Pediatrics
Epidemiology
Case Series of Severe Neurologic Sequelae of Ebola Virus Disease during Epidemic
Sierra Leone
lcsh:Medicine
medicine.disease_cause
Freetown
Cohort Studies
0302 clinical medicine
1108 Medical Microbiology
INFECTION
Medicine
CONTACTS
migraine
030212 general & internal medicine
Stroke
SURVIVORS
Psychiatric assessment
neurologic
meningitis
meningoencephalitis
Peripheral Nervous System Diseases
viral sequelae
34MH
3. Good health
Infectious Diseases
psychiatric
Cohort
Ebola
Synopsis
Female
Headaches
medicine.symptom
Life Sciences & Biomedicine
Cohort study
Microbiology (medical)
Adult
medicine.medical_specialty
34 Military Hospital
Migraine Disorders
Immunology
virus
Microbiology
Sierra leone
Sierra Leone
1117 Public Health and Health Services
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Young Adult
West Africa
Humans
ophthalmic
COHORT
viruses
lcsh:RC109-216
Epidemics
choriomeningioencephalitis
Ebola virus
Science & Technology
business.industry
ENCEPHALITIS
lcsh:R
Military Hospital 34
1103 Clinical Sciences
Hemorrhagic Fever
Ebola
medicine.disease
Migraine
GUINEA
business
030217 neurology & neurosurgery
34th Military Hospital
Zdroj: Emerging Infectious Diseases, Vol 24, Iss 8, Pp 1412-1421 (2018)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting neurologic criteria were invited from a cohort of 361 EVD survivors to attend a preliminary clinic. Those whose severe neurologic features were documented in the preliminary clinic were referred for specialist neurologic evaluation, ophthalmologic examination, and psychiatric assessment. Of 35 survivors with neurologic sequelae, 13 had migraine headache, 2 stroke, 2 peripheral sensory neuropathy, and 2 peripheral nerve lesions. Of brain computed tomography scans of 17 patients, 3 showed cerebral and/or cerebellar atrophy and 2 confirmed strokes. Sixteen patients required mental health follow-up; psychiatric disorders were diagnosed in 5. The 10 patients who experienced greatest disability had co-existing physical and mental health conditions. EVD survivors may have ongoing central and peripheral nervous system disorders, including previously unrecognized migraine headaches and stroke.
Databáze: OpenAIRE
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