Potentially Life-Threatening Cardiac Dysrhythmia in a Child with Selenium Deficiency and Phenylketonuria
| Autor: | Greeves Lg, Craig Bg, Carson Dj, D. McMaster |
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| Rok vydání: | 2008 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty chemistry.chemical_element Ventricular tachycardia Gastroenterology Selenium Selenium deficiency Phenylketonurias Tachycardia Internal medicine Humans Medicine Whole blood chemistry.chemical_classification business.industry Glutathione peroxidase Infant nutritional and metabolic diseases General Medicine Cardiac dysrhythmia medicine.disease Endocrinology chemistry Dietary treatment Pediatrics Perinatology and Child Health Etiology business Diet Therapy |
| Zdroj: | Acta Paediatrica. 79:1259-1262 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1990.tb11423.x |
| Popis: | Selenium deficiency is a frequent finding in children with phenylketonuria (PKU) receiving dietary treatment. We report the occurrence of episodic ventricular tachycardia in a 9-month-old infant with PKU. Serum selenium (Se), 0.13 mumol/l (normal range 0.28-1.12 mumol/l, mean +/- 2 SD), and whole blood glutathione peroxidase (GSHPX), 16 U/g Hb (normal range 19.5-34.3 U/g Hb, mean +/- 2 SD), were low. Auscultation of cardiac rhythm is recommended during the routine follow-up of young children with PKU. Se deficiency should be considered in the aetiology of a dysrhythmia and corrected with Se supplementation. |
| Databáze: | OpenAIRE |
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