Contribution of Myofascial Trigger Points to Migraine Symptoms
| Autor: | Emmanuele Tafuri, Alessandra Fabrizio, Andrea Mezzetti, Livio Di Ianni, Rosanna Lerza, Giannapia Affaitati, Antonella Savini, Domenico Lapenna, Maria Adele Giamberardino |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Pain Threshold Time Factors animal structures Adolescent Migraine Disorders Pain assessment Threshold of pain medicine Humans Muscle Skeletal Myofascial Pain Syndromes Pain Measurement Skin Analysis of Variance business.industry Middle Aged medicine.disease Electric Stimulation Peripheral Anesthesiology and Pain Medicine Nociception Neurology Migraine Evaluation Studies as Topic Anesthesia Hyperalgesia Anesthetic Female Pain Referred Neurology (clinical) Analysis of variance medicine.symptom business Anesthesia Local medicine.drug |
| Zdroj: | The Journal of Pain. 8:869-878 |
| ISSN: | 1526-5900 |
| DOI: | 10.1016/j.jpain.2007.06.002 |
| Popis: | This study evaluated the contribution of myofascial trigger points (TrPs) to migraine pain. Seventy-eight migraine patients with cervical active TrPs whose referred areas (RAs) coincided with migraine sites (frontal/temporal) underwent electrical pain threshold measurement in skin, subcutis, and muscle in TrPs and RAs at baseline and after 3, 10, 30, and 60 days; migraine pain assessment (number and intensity of attacks) for 60 days before and 60 days after study start. Fifty-four patients (group 1) underwent TrP anesthetic infiltration on the 3rd, 10th, 30th, and 60th day (after threshold measurement); 24 (group 2) received no treatment. Twenty normal subjects underwent threshold measurements in the same sites and time points as patients. At baseline, all patients showed lower than normal thresholds in TrPs and RAs in all tissues (P < .001). During treatment in group 1, all thresholds increased progressively in TrPs and RAs (P < .0001), with sensory normalization of skin/subcutis in RAs at the end of treatment; migraine pain decreased (P < .001). Threshold increase in RAs and migraine reduction correlated linearly (.0001 < P < .006). In group 2 and normal subjects, no changes occurred. Cervical TrPs with referred areas in migraine sites thus contribute substantially to migraine symptoms, the peripheral nociceptive input from TrPs probably enhancing the sensitiza- tion level of central sensory neurons. Perspective: This article shows the beneficial effects of local therapy of active myofascial trigger points(TrPs)onmigrainesymptomsinpatientsinwhommigrainesitescoincidewiththereferredareas of the TrPs. These results suggest that migraine pain is often contributed to by myofascial inputs that enhance the level of central neuronal excitability. |
| Databáze: | OpenAIRE |
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