Outcome of investigations for postmenopausal vaginal bleeding in women under the age of 50years
| Autor: | Timothy J. Duncan, Joaquin J. Nieto, Edward Morris, Simon G. Crocker, Nikolaos Burbos, Patrick Musonda |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Cross-sectional study Endometrium Risk Factors medicine Carcinoma Humans Vaginal bleeding Aged Retrospective Studies Gynecology medicine.diagnostic_test business.industry Incidence Endometrial cancer Incidence (epidemiology) Age Factors Obstetrics and Gynecology Retrospective cohort study Middle Aged medicine.disease United Kingdom Endometrial Neoplasms Postmenopause Cross-Sectional Studies medicine.anatomical_structure Oncology Female Uterine Hemorrhage medicine.symptom business Endometrial biopsy |
| Zdroj: | Gynecologic Oncology. 125:120-123 |
| ISSN: | 0090-8258 |
| DOI: | 10.1016/j.ygyno.2011.12.453 |
| Popis: | Objective The objective of this study is to determine the incidence of endometrial cancer in young postmenopausal women presenting with vaginal bleeding. Methods Cross-sectional study of postmenopausal women presenting with vaginal bleeding in a gynaecological oncology centre in the United Kingdom. All women underwent transvaginal ultrasound scanning (TVS) as the initial investigation tool to evaluate the endometrium. Endometrial biopsy was performed only in cases where endometrial thickness measured equal to or greater than 5mm. The patients were divided into two groups based on their age: less than 50years (Group A) and 50years or older (Group B). Results Over a 57-month period, 4454 women were investigated for postmenopausal vaginal bleeding. Of these, 259 (5.8%) women were diagnosed with endometrial carcinoma. 260 (5.8%) women were younger than 50years. Endometrial biopsy was not performed in 130 women in Group A that had an endometrial thickness measurement of less than 5mm on ultrasonography. With a median follow-up period of 3 (1–5) years, we found no cases of endometrial cancer in women under the age of 50 that did not undergo endometrial biopsy at the time of initial evaluation. Overall, no cases of endometrial cancer were diagnosed in postmenopausal women under the age of 50years. Conclusions We found no cases of endometrial cancer amongst 260 women presenting with postmenopausal vaginal bleeding under the age of 50years. These women could be investigated on a less urgent basis depending on the available resources. |
| Databáze: | OpenAIRE |
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