Consensus Guidelines from The American Society of Peritoneal Surface Malignancies on Standardizing the Delivery of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Patients in the United States
| Autor: | Jesus Esquivel, Paul F. Mansfield, Jason M. Foster, Daniel M. Labow, T. Blazer, Robert M. Barone, Joseph J. Skitzki, Richard E. Royal, John H. Stewart, J. Spellman, Robert P. Sticca, Benjamin D.L. Li, James F. Pingpank, Laura A. Lambert, George I. Salti, H.R. Alexander, Edward A. Levine, Reynaldo Garcia, A. Bastidas, N. J. Espat, Lawrence E. Harrison, F. Attiyeh, Armando Sardi, K. Y. Chung, Richard A. Hoefer, Andrew M. Lowy, R. Adbel-Misih, Colette R. Pameijer, M. Quinones, Garrett M. Nash, Quyen D. Chu, E. Ong, Keith Fournier, Kiran K. Turaga, Michael D. Goodman, Perry Shen, Nader Hanna, John M. Kane, Matthew P. Holtzman, Michael A. Morse, David L. Bartlett, L. Dominguez-Parra, Nicholas J. Petrelli |
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| Rok vydání: | 2013 |
| Předmět: |
Societies
Scientific medicine.medical_specialty Consensus Peritoneal surface Colorectal cancer medicine.medical_treatment Surgical oncology Antineoplastic Combined Chemotherapy Protocols Humans Medicine Combined Modality Therapy Peritoneal Neoplasms Chemotherapy business.industry General surgery Cancer Hyperthermia Induced medicine.disease Oxaliplatin Surgery Oncology Chemotherapy Cancer Regional Perfusion Practice Guidelines as Topic Hyperthermic intraperitoneal chemotherapy Colorectal Neoplasms business medicine.drug |
| Zdroj: | Annals of Surgical Oncology. 21:1501-1505 |
| ISSN: | 1534-4681 1068-9265 |
| DOI: | 10.1245/s10434-013-3061-z |
| Popis: | The American Society of Peritoneal Surface Malignancies (ASPSM) is a consortium of cancer centers performing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC). This is a position paper from the ASPSM on the standardization of the delivery of HIPEC.A survey was conducted of all cancer centers performing HIPEC in the United States. We attempted to obtain consensus by the modified method of Delphi on seven key HIPEC parameters: (1) method, (2) inflow temperature, (3) perfusate volume, (4) drug, (5) dosage, (6) timing of drug delivery, and (7) total perfusion time. Statistical analysis was performed using nonparametric tests.Response rates for ASPSM members (n = 45) and non-ASPSM members (n = 24) were 89 and 33 %, respectively. Of the responders from ASPSM members, 95 % agreed with implementing the proposal. Majority of the surgical oncologists favored the closed method of delivery with a standardized dual dose of mitomycin for a 90-min chemoperfusion for patients undergoing cytoreductive surgery for peritoneal carcinomatosis of colorectal origin.This recommendation on a standardized delivery of HIPEC in patients with colorectal cancer represents an important first step in enhancing research in this field. Studies directed at maximizing the efficacy of each of the seven key elements will need to follow. |
| Databáze: | OpenAIRE |
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