Zomepirac Sodium in the Treatment of Primary Dysmenorrhea Syndrome
| Autor: | Penny Wise Budoff |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Prostaglandin Antagonists Placebo Gastroenterology Gastrointestinal disturbances Double-Blind Method Dysmenorrhea Internal medicine Activities of Daily Living medicine Zomepirac Humans Pyrroles Tolmetin Adverse effect Abdominal cramping Zomepirac sodium Analgesics Clinical Trials as Topic business.industry General Medicine Crossover study Surgery Research Design Population study Female business medicine.drug |
| Zdroj: | New England Journal of Medicine. 307:714-719 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm198209163071203 |
| Popis: | Zomepirac sodium was compared with placebo for relief of primary dysmenorrhea syndrome in a double-blind, crossover study of 47 patients. The agents were taken in three separate crossovers during six menstrual periods. Abdominal cramping and 25 other symptoms of dysmenorrhea syndrome were evaluated daily. Zomepirac was significantly more effective than placebo in relieving 12 of 13 primary symptoms and 6 of 13 associated symptoms (P≤0.05). While taking zomepirac, patients were able to continue normal activities on a significantly higher proportion of days (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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