The Lymphocyte-to-monocyte Ratio Is an Independent Prognostic Indicator in Pancreatic Head Cancer that Correlates With Obstructive Jaundice
| Autor: | Michinori Iwamura, Tomoe Katoh, Masahiro Mitsuyoshi, Masahiko Onoda, Kumiko Yoshida, Masahiro Takeuchi, Akira Furutani, Kazuaki Kawano |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Multivariate analysis Lymphocyte medicine.medical_treatment Systemic inflammation Gastroenterology Monocytes Internal medicine medicine Humans Lymphocytes Risk factor Survival rate Aged Retrospective Studies Aged 80 and over business.industry Monocyte General Medicine Middle Aged Pancreaticoduodenectomy Prognosis Survival Analysis Pancreatic Neoplasms Jaundice Obstructive medicine.anatomical_structure Oncology Obstructive jaundice Female medicine.symptom business |
| Zdroj: | Anticancer research. 40(6) |
| ISSN: | 1791-7530 |
| Popis: | Background/aim Several indicators of systemic inflammation have been reported to predict the outcomes of patients with malignant tumors but have not been fully investigated. The aim of this study was to evaluate whether the preoperative lymphocyte-to-monocyte ratio (LMR) can predict the outcomes of patients with pancreatic head cancer. Patients and methods We studied 32 patients who underwent curative surgery for pancreatic head cancer in our hospital between 2006 and 2016. Patients were classified into high and low groups according to their LMR. Results The low LMR group had a significantly lower survival rate than the high LMR group (p=0.0313). A multivariate analysis showed that the pretreatment LMR (p=0.01) was an independent risk factor for cancer-related death. The LMR was correlated with obstructive jaundice (p=0.001). Conclusion Preoperative LMR is a significant predictor of the outcome after pancreaticoduodenectomy in patients with pancreatic head cancer. |
| Databáze: | OpenAIRE |
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