Nasal or Temporal Internal Limiting Membrane Flap Assisted by Sub-Perfluorocarbon Viscoelastic Injection for Macular Hole Repair
| Autor: | Ying-Jiun Chong, Hung-Da Chou, Yih-Shiou Hwang, Wei-Chi Wu, Kuan-Jen Chen, Laura Liu, Ling Yeung, Yen-Po Chen, Chi-Chun Lai, Wee Min Teh |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Novel technique medicine.medical_specialty Visual acuity genetic structures Liquid injection medicine.medical_treatment Vitrectomy Endotamponade Basement Membrane Surgical Flaps 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ophthalmology medicine Humans Retinal thinning Macular hole Retrospective Studies 030304 developmental biology Fluorocarbons 0303 health sciences business.industry Internal limiting membrane Retinal Middle Aged Retinal Perforations medicine.disease eye diseases Treatment Outcome chemistry 030221 ophthalmology & optometry Female sense organs Injections Intraocular medicine.symptom business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | American Journal of Ophthalmology. 223:296-305 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/j.ajo.2020.09.023 |
| Popis: | To compare the outcomes between using a nasal and a temporal inverted internal limiting membrane (ILM) flap both assisted by a novel technique in repairing a full-thickness macular hole (FTMH).Retrospective interventional case series.Thirty-nine eyes from 39 patients with a FTMH600 μm were included from a single institution. All patients underwent vitrectomy using a semicircular single-layered ILM inverted flap assisted by a sub-perfluorocarbon liquid injection of ophthalmic viscoelastic device (OVD) technique. Best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography were used to compare outcomes between nasal (n = 19) and temporal (n = 20) groups.At 6 months postoperatively, all FTMHs closed and BCVA were significantly improved. Overall, 36 eyes (92%) achieved U-shaped closure, and ellipsoid zone restoration was noted in 24 eyes (62%). An ILM flap was present in 29 eyes (74%) and 86% remained single-layered. There were significantly more deep inner retinal dimples in the temporal group (35%) compared with 5% in the nasal group (P = .04), but these were unrelated to BCVA. Significant retinal thinning in the temporal outer sub-field was noted in the temporal group and was negatively correlated with BCVA (rho [ρ]: - .53; P = .03). No significant postoperative retinal displacement was noted in either group.The technique of using sub-perfluorocarbon liquid injection of OVD secured single-layered flaps intraoperatively and postoperatively. Both the nasal and temporal inverted ILM flaps repaired FTMH and improved visual acuity. However, both temporal macular thinning and deep inner retinal dimples were significantly greater in the temporal group. |
| Databáze: | OpenAIRE |
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