Reversible paralysis with status asthmaticus, steroids, and pancuronium: clinical electrophysiological correlates
| Autor: | Gordon Mackie, Heather Stewart, Tian-Xi Jiang, Jeremy Road, Andrew Eisen |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Weakness Physiology medicine.medical_treatment Status Asthmaticus Electromyography Methylprednisolone law.invention Cellular and Molecular Neuroscience law Physiology (medical) medicine Paralysis Humans Pancuronium Myopathy Glucocorticoids Mechanical ventilation Neuromuscular Blockade medicine.diagnostic_test business.industry Muscles Middle Aged Neuromuscular Blocking Agents Intensive care unit Anesthesia Female Neurology (clinical) medicine.symptom business |
| Zdroj: | Musclenerve. 20(12) |
| ISSN: | 0148-639X |
| Popis: | Prolonged neuromuscular weakness has been identified after neuromuscular blockade in intensive care unit patients on mechanical ventilation. Previously reported electromyographic studies in these patients documented both neurogenic features and features consistent with a myopathy. We recorded sequential electrophysiological parameters during recovery from neuromuscular blockade in 5 patients with clinical weakness. An evolving pattern was identified. The early features were in keeping with previous reports of neurogenic changes, and this evolved into features consistent with a primary myopathy. Several potential underlying mechanisms are discussed. |
| Databáze: | OpenAIRE |
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