Characteristics of complement consumption by atopic allergens
| Autor: | C.L.H. Guikers, J. Van Rijswijk-Verbeek, L. Berrens |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Hypersensitivity
Immediate Globulin Physical Therapy Sports Therapy and Rehabilitation medicine.disease_cause Hemolysis Microbiology Allergen Complement C1 medicine Humans Complement component 5 biology Complement component 2 Chemistry Rehabilitation Esterases Complement C5 Dust General Medicine Complement C3 Complement System Proteins Tosylarginine Methyl Ester Allergens Complement C2 medicine.disease In vitro respiratory tract diseases Complement (complexity) Immunology biology.protein Chromatography Gel House dust allergen Serum Globulins |
| Zdroj: | Immunochemistry. 13(5) |
| ISSN: | 0019-2791 |
| Popis: | Purified house dust allergen was chosen as a prototype of atopic allergens capable of consuming human haemolytic complement in vitro . C hu inactivation in dilute serum proceeded by way of the classical sequence. The major effect of allergen was on C1 and C2: negligible loss of effective C3 and C5 occurred. Preliminary isolation studies and indirect evidence indicates the destruction of effective C1 to be mediated by a euglobulin macromolecular serum factor. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|