A case report of parotid mammary analogue secretory carcinoma and reviews
| Autor: | Teagan Thorson, Jiankun Tong, Roger Zhu, Larry J. Shemen, William H. Rodgers, Luona Sun, Jerry Huo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Head-and-neck Asymptomatic Article Acinic cell carcinoma 03 medical and health sciences 0302 clinical medicine Case report medicine Parotid Salivary Cancer business.industry Standard treatment Parotidectomy medicine.disease Facial nerve Radiation therapy Dissection 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Radiology medicine.symptom business |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • Mammary analog secretory carcinoma (MASC) is a new concept in diagnosis of head and neck tumors. • MASC is often misdiagnosed as other tumors such as salivary acinic cell carcinoma. • Management of MASC follows treatment of low-grade salivary gland neoplasm which is radical surgical excision. • More advanced MASC are treated with radical excision, neck dissection, radiation and chemotherapy. • No standard protocol has been established due to rarity of the disease. Introduction Mammary analog secretory carcinoma (MASC) is a new diagnosis of head and neck tumors first reported in 2010. It was often misdiagnosed as salivary acinic cell carcinoma (AciCC). We present a patient with an asymptomatic parotid tumor that underwent deep lobe parotidectomy and postoperative radiation therapy. The final pathology showed MASC. Case presentation A 57-year-old male presented with an asymptomatic enlarging right parotid mass. A CT neck with IV contrast showed a 1.2 cm heterogeneously enhancing mass in the center of the right parotid gland without extraparotid extension. An FNA showed an epithelial neoplasm with papillary features. The patient underwent a right deep lobe parotidectomy with facial nerve dissection. The final pathology confirmed the diagnosis of MASC. He subsequently completed a 6-week course of radiation therapy and remained asymptomatic at his 30-month follow up. Discussion/conclusion Although MASC is considered a low-grade tumor in most cases, recurrence and disseminated disease are not uncommon. No standard treatment protocol has been established. This report aims to enhance the awareness of this diagnosis and provide a review of current treatments for head and neck oncology care providers. |
| Databáze: | OpenAIRE |
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