A Revised Model for the Calculation of Absorbed Energy in the Gastrointestinal Tract
| Autor: | J W, Poston, K A, Kodimer, W E, Bolch |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Photons
Radionuclide Gastrointestinal tract Photon Epidemiology Chemistry business.industry Health Toxicology and Mutagenesis Electrons Radiation Dosage Computational physics Committed dose equivalent Internal dose Energy absorbing Humans Dosimetry Radiology Nuclear Medicine and imaging Nuclear medicine business Digestive System Monte Carlo Method Target organ |
| Zdroj: | Health Physics. 71:307-314 |
| ISSN: | 0017-9078 |
| Popis: | The goal of this research was to develop a more complete gastrointestinal (GI) tract model for use in internal dose assessment. This paper summarizes the development of a revised mathematical model of the GI tract. The current GI tract model assumes the wall can be represented as a single soft tissue layer without regard to the radiosensitivity of the cells. The goal of the GI tract revision was to develop geometric regions that separate the radiosensitive cells from the less radiosensitive cells. Once the model was revised, it was coded into the Electron Gamma Shower 4 (EGS4) computational package for calculation of photon and electron absorbed fraction values. Photon absorbed fraction values were calculated for twelve discrete energies. For the photon absorbed fraction calculations, the EGS4 program was run so that secondary particles created in photon interactions were followed using the electron tracking capabilities of EGS4. The results of the photon absorbed fraction calculations provided better estimates of the energy deposited in the radiosensitive cells when the target organ was the source. In cases where the target organ was not the source, the photon absorbed fraction values did not provide better estimates than those obtained using the current GI tract model. An increase in the number of photon histories should provide better estimates of the photon absorbed fraction for these cases. Electron absorbed fraction values also were calculated for twelve discrete electron energies. The results of these calculations provided the expected pattern of energy deposition and better estimates than those currently available. The annual limit on intake was recalculated for a single radionuclide to demonstrate the affect of these improved absorbed fraction values on internal dose assessment. The radionuclide was selected for two reasons: 1) it was a beta emitting radionuclide; and 2) the annual limit on intake for ingestion was based on the non-stochastic committed dose equivalent limit to the lower large intestine. The calculated annual limit on intake was found to be three times greater than the annual limit on intake provided in ICRP Publication 30. There are many radionuclides that have a section of the GI tract as the limiting organ for ingestion. It is expected that the annual limit on intake value for these radionuclides would increase when the revised GI tract model is employed for internal dose assessment. |
| Databáze: | OpenAIRE |
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