Ibuprofen analysis in blood samples by palladium particles-impregnated sodium montmorillonite electrodes: Validation using high performance liquid chromatography
| Autor: | H. Nasrellah, Mina Bakasse, Sara Lahrich, K. Hnini, Y. El Bouabi, Abdelfettah Farahi, W. Boumya, M.A. El Mhammedi, H. Hammani, A. Loudiki, M. Zeroual, M. Achak |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Sodium chemistry.chemical_element Bioengineering Ibuprofen 02 engineering and technology 01 natural sciences High-performance liquid chromatography Biomaterials chemistry.chemical_compound X-Ray Diffraction Limit of Detection medicine Electrochemistry Humans Electrodes Chromatography High Pressure Liquid Chromatography organic chemicals 010401 analytical chemistry Reproducibility of Results 021001 nanoscience & nanotechnology Quantitative determination 0104 chemical sciences Montmorillonite chemistry Mechanics of Materials Electrode Bentonite Linear Models Differential pulse voltammetry 0210 nano-technology Palladium medicine.drug |
| Zdroj: | Materials scienceengineering. C, Materials for biological applications. 69 |
| ISSN: | 1873-0191 |
| Popis: | The electrochemical detection of ibuprofen has been studied on Palladium-Montmorillonite (Mt) modified carbon paste electrode using differential pulse voltammetry. The optimization of the modifier preparation and the instrumental parameters was investigated. The results indicate that ibuprofen oxidation was favored in the presence of Pd–PdO particles. The quantitative determination of ibuprofen was statistically analyzed and validated using HPLC method. The detection and quantification limits, specificity and precision were found to be acceptable. Finally, the developed method was successfully applied for ibuprofen determination in human blood samples. |
| Databáze: | OpenAIRE |
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