Quadrupole ion storage tandem mass spectrometry and high-resolution mass spectrometry: complementary application in the measurement of 2,3,7,8-chlorine substituted dibenzo-p-dioxins and dibenzofurans in US foods
| Autor: | Virginia Spencer, Mark Harris, Robert Glidden, Douglas G. Hayward, Jim R Holcomb, Paige Wilson |
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| Rok vydání: | 2001 |
| Předmět: |
Quality Control
Polychlorinated Dibenzodioxins Environmental Engineering Eggs Health Toxicology and Mutagenesis chemistry.chemical_element Food Contamination Mass spectrometry Tandem mass spectrometry Mass Spectrometry Cheese Chlorine Animals Humans Soil Pollutants Environmental Chemistry Shellfish Benzofurans Detection limit Persistent organic pollutant Chromatography Fishes Public Health Environmental and Occupational Health General Medicine General Chemistry Dibenzofurans Polychlorinated Pollution Rockfish Congener chemistry Environmental chemistry |
| Zdroj: | Chemosphere. 43:407-415 |
| ISSN: | 0045-6535 |
| DOI: | 10.1016/s0045-6535(00)00388-x |
| Popis: | The US Food and Drug Administration has simultaneously utilized both high-resolution mass spectrometry (HRMS) and quadrupole ion storage tandem mass spectrometry (QISTMS) in the measurement of polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) in 147 food samples collected in 1998 and 1999 in the US. In 1998, 20 egg samples, six scallop, 10 blue crab, eight American lobster, 10 pollack, 15 striped bass, five rockfish, 10 crawfish, seven aqua-cultured and 13 wild-caught salmon, along with 19 cream and 18 mozzarella cheese samples were measured for PCDD/Fs. QISTMS provided limits of detection (LODs) close to those produced using HRMS for many congeners in 56 samples analyzed by both techniques in 1998 and three salmon and three striped bass collected in 1999. The I-TEQs of the mean levels for measured congeners in 40 samples of fish and shellfish and 16 cheese and eggs from 1998 analyzed by HRMS and QISTMS were 0.99 and 1.1 ng/kg wet weight, respectively. The I-TEQ for mean congener levels in the 40 fish and shellfish measured by HRMS was 1.4 ng/kg wet weight. A higher sample throughput with greater data quality at a lower cost is achievable by using both QISTMS and HRMS. |
| Databáze: | OpenAIRE |
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