Radial Glia in Echinoderms
| Autor: | Vladimir S. Mashanov, Olga R. Zueva |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Cell type Neurogenesis Chordate Article 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Developmental Neuroscience biology.animal Animals Homeostasis Deuterostome biology Regeneration (biology) Vertebrate biology.organism_classification Biological Evolution Nerve Regeneration 030104 developmental biology Echinoderm Evolutionary biology Neuroglia Neural development 030217 neurology & neurosurgery Echinodermata |
| Zdroj: | Dev Neurobiol |
| ISSN: | 1932-846X 1932-8451 |
| DOI: | 10.1002/dneu.22659 |
| Popis: | Radial glial cells are crucial in vertebrate neural development and regeneration. It has been recently proposed that this neurogenic cell type might be older than the chordate lineage itself and might have been present in the last common deuterostome ancestor. Here, we summarize the results of recent studies on radial glia in echinoderms, a highly regenerative phylum of marine invertebrates with shared ancestry to chordates. We discuss the involvement of these cells in both homeostatic neurogenesis and post-traumatic neural regeneration, compare the features of radial glia in echinoderms and chordates to each other, and review the molecular mechanisms that control differentiation and plasticity of the echinoderm radial glia. Overall, studies on echinoderm radial glia provide a unique opportunity to understand the fundamental biology of this cell type from evolutionary and comparative perspectives. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text