| Autor: |
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22398303.v1 |
| Popis: |
PDF file - 188K, Sequencing of UCR41 and flanking regions: UCR41 is a 217-bp-long ultra-conserved region depicted in dark green. The gray bar indicates the extremely conserved sequence. The region is flanked by two SNPs that are frequent in the European population (blue arrows). The black curve indicates the mutability, which is higher in non-conserved regions compared with conserved segments. The black bars illustrate the 5 overlapping amplicons used for amplification. Mutations identified in our samples are indicated with red arrows. The genomic coordinates refer to the hg18 assembly of the human genome. (The graph is reproduced with permission from De Grassi et al.) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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