Early detection and integrated care for adolescents and young adults with psychotic disorders: the ACCESS III study

Autor: Jürgen Gallinat, Vivien Niehaus, Anne Karow, Daniel Schöttle, Klaus Wiedemann, Charlotte Gagern, Friederike Ruppelt, Linus Wittmann, Anne Daubmann, Thomas Bock, Anne-Lena Falk, Liz Rietschel, Benno G. Schimmelmann, Luise Antonia Nawara, Hans-Peter Unger, Karl Wegscheider, Sabine Ott, Georg Romer, Martin Lambert, Michael Schulte-Markwort, Anja Rohenkohl, Mary Sengutta, Christoph U. Correll, G Sarikaya, Britta Galling, Daniel Luedecke
Rok vydání: 2017
Předmět:
Zdroj: Acta Psychiatrica Scandinavica. 136:188-200
ISSN: 0001-690X
DOI: 10.1111/acps.12762
Popis: Objective The objective of the study was to investigate whether a combined intervention composed of early detection plus integrated care (EDIC) enhances outcomes in patients with early psychosis compared to standard care (SC). Methods ACCESS III is a prospective non-randomized historical control design 1-year study examining the efficacy of EDIC (n = 120) vs. SC (n = 105) in patients aged 12–29 years. Primary outcome was the rate of ≥6 months combined symptomatic and functional remission. Additional outcomes comprised the reduction of DUP and course of psychopathology, functioning, quality of life, and satisfaction with care. Results In observed cases, 48.9% in the EDIC and 15.2% in the SC group reached the primary endpoint. Remission was predicted by EDIC (OR = 6.8, CI: 3.15–14.53, P
Databáze: OpenAIRE