INTERSTITIAL CELL TUMOR OF THE TESTIS. STUDY OF A 5-YEAR-OLD BOY WITH PSEUDO-PRECOCIOUS PUBERTY*
| Autor: | Charles D. Cook, Benjamin H. Landing, Aniela S. Zygmuntowicz, Robert E. Gross |
|---|---|
| Rok vydání: | 1952 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Urinary system Clinical Biochemistry Puberty Precocious Biochemistry Endocrinology Testicular Neoplasms Neoplasms Edema Internal medicine Testis Scrotum medicine Humans Precocious puberty Sexual Maturation Acne business.industry Puberty Biochemistry (medical) medicine.disease Axilla medicine.anatomical_structure Leydig Cell Tumor medicine.symptom business Penis |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 12:725-734 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-12-6-725 |
| Popis: | THE interstitial cells of the testis, which were first described by Leydig (1), occasionally may give rise to tumors. Eight such cases occurring in childhood have been described in the literature (2–9). In the pediatric age group these tumors occur mostly during the fifth and sixth years of life and apparently are invariably associated with signs of precocious masculinization. The present report describes an additional case of pseudo-precocious puberty due to a testicular interstitial cell tumor in a 5-year-old boy, and gives quantitative and qualitative information concerning his urinary steroid excretion. Report of Case This white boy, aged 5 3/12 years, was admitted for study because of precocious masculinization. Eight months earlier, it had been noted that his voice had become deeper, that he had suddenty begun to gain rapidly in height and weight, and that his penis was becoming larger than normal. At the same time, acne was seen on his face. Seven months before admission, pubic and axillary hair we... |
| Databáze: | OpenAIRE |
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