Dengue and Chikungunya fever among viral diseases in outpatient febrile children in Kilosa district hospital, Tanzania
| Autor: | Paul Gwakisa, Mbaraka Amuri, Fausta Mosha, Joseph P. Mugasa, Majige Selemani, Beatrice Chipwaza, Steve D. Ngatunga |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Adolescent Fever lcsh:RC955-962 viruses Dengue virus medicine.disease_cause Tanzania Dengue fever Dengue Emerging and Re-emerging Infectious Diseases Rotavirus Outpatients parasitic diseases medicine Medicine and Health Sciences Outpatient clinic Humans Chikungunya Child Disease burden business.industry lcsh:Public aspects of medicine Public Health Environmental and Occupational Health Biology and Life Sciences lcsh:RA1-1270 medicine.disease Infectious Diseases Cross-Sectional Studies Child Preschool Immunology Etiology Chikungunya Fever Female business Malaria Research Article |
| Zdroj: | PLoS Neglected Tropical Diseases, Vol 8, Iss 11, p e3335 (2014) PLoS Neglected Tropical Diseases |
| ISSN: | 1935-2735 1935-2727 |
| Popis: | Introduction Viral etiologies of fever, including dengue, Chikungunya, influenza, rota and adeno viruses, cause major disease burden in tropical and subtropical countries. The lack of diagnostic facilities in developing countries leads to failure to estimate the true burden of such illnesses, and generally the diseases are underreported. These diseases may have similar symptoms with other causes of acute febrile illnesses including malaria and hence clinical diagnosis without laboratory tests can be difficult. This study aimed to identify viral etiologies as a cause of fever in children and their co-infections with malaria. Methods A cross sectional study was conducted for 6 months at Kilosa district hospital, Tanzania. The participants were febrile children aged 2–13 years presented at the outpatient department. Diagnostic tests such as IgM and IgG ELISA, and PCR were used. Results A total of 364 patients were enrolled, of these 83(22.8%) had malaria parasites, 76 (20.9%) had presumptive acute dengue infection and among those, 29(38.2%) were confirmed cases. Dengue was more likely to occur in children ≥ 5 years than in Author Summary Viral etiologies of fever, such as dengue, Chikungunya, influenza, rotaviruses, and adenoviruses contribute to substantial morbidity and mortality particularly in children in the tropical and subtropical countries. Despite their importance, the true burden of viral etiologies of fever in Tanzania is not known, and in most cases these diseases are unrecognized and treated as malaria. This study aimed to identify viral etiologies as a cause of fever in children and co-infections among viral diseases and malaria. A total of 364 febrile children were enrolled, of these, 83 (22.8%) had malaria, 76(20.9%) had presumptive acute dengue, among those, 29(38.2%) were confirmed cases. Dengue was more likely to occur in children aged ≥ 5 years than in |
| Databáze: | OpenAIRE |
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