Behavior- and Modality-General Representation of Confidence in Orbitofrontal Cortex
| Autor: | Adam Kepecs, Paul Masset, Armin Lak, Torben Ott, Junya Hirokawa |
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| Rok vydání: | 2020 |
| Předmět: |
Time Factors
Process (engineering) Decision Making Sensation Prefrontal Cortex Metacognition Biology Choice Behavior Models Biological Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Stimulus modality Task Performance and Analysis Animals Reinforcement learning Rats Long-Evans 030304 developmental biology Abstraction (linguistics) Neurons Behavior 0303 health sciences Modality (human–computer interaction) Representation (systemics) Orbitofrontal cortex 030217 neurology & neurosurgery Cognitive psychology |
| Zdroj: | Cell |
| ISSN: | 0092-8674 |
| Popis: | Summary Every decision we make is accompanied by a sense of confidence about its likely outcome. This sense informs subsequent behavior, such as investing more—whether time, effort, or money—when reward is more certain. A neural representation of confidence should originate from a statistical computation and predict confidence-guided behavior. An additional requirement for confidence representations to support metacognition is abstraction: they should emerge irrespective of the source of information and inform multiple confidence-guided behaviors. It is unknown whether neural confidence signals meet these criteria. Here, we show that single orbitofrontal cortex neurons in rats encode statistical decision confidence irrespective of the sensory modality, olfactory or auditory, used to make a choice. The activity of these neurons also predicts two confidence-guided behaviors: trial-by-trial time investment and cross-trial choice strategy updating. Orbitofrontal cortex thus represents decision confidence consistent with a metacognitive process that is useful for mediating confidence-guided economic decisions. |
| Databáze: | OpenAIRE |
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