Comparison of screening strategies with two new tests to score and diagnose varices needing treatment

Autor: Paul Calès, Federico Ravaioli, Arthur Berger, Oana Farcau, Davide Festi, Horia Stefanescu, Carole Vitellius, Pierre Nahon, Christophe Bureau, Nathalie Ganne-Carriè, Annalisa Berzigotti, Victor de Ledinghen, Salvatore Petta
Přispěvatelé: Calès, Paul, Ravaioli, Federico, Berger, Arthur, Farcau, Oana, Festi, Davide, Stefanescu, Horia, Vitellius, Carole, Nahon, Pierre, Bureau, Christophe, Ganne-Carriè, Nathalie, Berzigotti, Annalisa, de Ledinghen, Victor, Petta, Salvatore
Rok vydání: 2022
Předmět:
Zdroj: Calès, Paul; Ravaioli, Federico; Berger, Arthur; Farcau, Oana; Festi, Davide; Stefanescu, Horia; Vitellius, Carole; Nahon, Pierre; Bureau, Christophe; Ganne-Carriè, Nathalie; Berzigotti, Annalisa; de Ledinghen, Victor; Petta, Salvatore (2022). Comparison of screening strategies with two new tests to score and diagnose varices needing treatment. Clinics and research in hepatology and gastroenterology, 46(7), p. 101925. Elsevier Masson 10.1016/j.clinre.2022.101925
ISSN: 2210-741X
DOI: 10.1016/j.clinre.2022.101925
Popis: Background and aims: We aimed to improve non-invasive screening of varices needing treatment (VNT) and compare different screening strategies. Methods: 2,290 patients with chronic liver disease were included in a retrospective study. Etiologies were: virus: 50.0%, NAFLD: 29.5%, alcohol: 20.5%, VNT: 14.9%. Test descriptors were performance (spared endoscopy) and safety (missed VNT). VNT tests were evaluated according to their safety levels either for individual screening (95% negative predictive value (NPV)), population screening (95% sensitivity) or undifferentiated screening (100% sensitivity/NPV) without missed VNT. The tests provided three categories: missed VNT
Databáze: OpenAIRE