Soft filamentous woven polyester arterial prosthesis from China
| Autor: | Pan Chin, Li Cilan, Rao Tian-Jian, Rui Jusheng, Martin W. King, Robert Guidoin, Daniel Marceau, Qian Xiaoping, Lin Chenhua, Brigitta Badour, Cheng Haimin, Paul-Emile Roy |
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| Rok vydání: | 1991 |
| Předmět: |
Materials science
Polyesters Biophysics Aorta Thoracic Biocompatible Materials Bioengineering Arterial prosthesis Permeability Biomaterials Dogs Blood loss Materials Testing Highly porous Animals North American origin Wound Healing Biomaterial Arteries Hemostasis Surgical Blood Vessel Prosthesis Smooth surface Polyester Mechanics of Materials Microscopy Electron Scanning Ceramics and Composites Endothelium Vascular Tissue ingrowth Biomedical engineering |
| Zdroj: | Biomaterials. 12:335-344 |
| ISSN: | 0142-9612 |
| DOI: | 10.1016/0142-9612(91)90043-a |
| Popis: | Woven polyester arterial prostheses have traditionally been known for their tight construction and smooth surface which has limited their healing capacity and resulted in poor attachment of their internal and external capsules. A new woven prototype has recently been developed in the Peoples' Republic of China. Among its unique features are its high physical porosity, softness and flexibility. This study undertook a series of in vitro tests to characterize its structure and physical properties in comparison with four commercial polyester grafts of North American origin. In addition, an animal trial was completed in which the new prototype was implanted as an infrarenal aortic substitute in 20 dogs for periods ranging from 4 h to 12 month. The in vitro tests confirmed a unique lightweight, highly porous, satin weave construction. Because of its high water permeability, preclotting was necessary before implantation. Once preclotted and installed, no significant blood loss was observed, and 19 of the 20 grafts remained patent at the sacrifice. Rapid full-width healing was achieved with tightly bound capsules, and more extensive tissue ingrowth was observed. Further work is needed to evaluate its long-term durability as an arterial substitute. |
| Databáze: | OpenAIRE |
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