The Optimal Cutoff Level of D-Dimer during Pregnancy to Exclude Deep Vein Thrombosis, and the Association between D-Dimer and Postpartum Hemorrhage in Cesarean Section Patients
| Autor: | Hiroaki Kobayashi, Shinichi Togami, Tomonori Hamada, Yuji Orita, Tsutomu Douchi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Optimal cutoff Deep vein Fibrin Fibrinogen Degradation Products 03 medical and health sciences 0302 clinical medicine Blood loss Pregnancy D-dimer Humans Medicine cardiovascular diseases 030212 general & internal medicine Retrospective Studies Venous Thrombosis Cesarean Section business.industry Obstetrics Incidence (epidemiology) Postpartum Hemorrhage General Medicine medicine.disease Thrombosis medicine.anatomical_structure Gestation Female business Biomarkers |
| Zdroj: | The Kurume Medical Journal. 66:107-114 |
| ISSN: | 1881-2090 0023-5679 |
| Popis: | OBJECTIVE The main purpose was to clarify the optimal D-dimer cutoff level during pregnancy to exclude deep vein thrombosis (DVT) prior to Cesarean section. The secondary purpose was to determine whether D-dimer can predict severe postpartum hemorrhage (PPH) in Cesarean section patients. METHODS Two hundred and seventy eight elective Cesarean section cases were enrolled. Clinical factors and blood parameters at 34-37 weeks of gestation were analyzed. To detect DVT, lower extremities veins were examined using color Doppler ultrasonography in cases with D-dimer level ≥ 1.5 μg/mL. In addition, postpartum blood loss amounts during Cesarean section were recorded. RESULTS Five DVT cases occurred in 250 singleton pregnancies, and 2 DVT cases occurred in 28 twin pregnancies. The overall incidence of DVT was 2.5%. The D-dimer level was higher in DVT cases than in non-DVT cases (3.84±1.97 vs. 2.31±1.48 μg/mL, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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