Colchicine may be of therapeutic benefit in prurigo pigmentosa

Autor:	Vasfiye Demir, Ibrahim Ibiloglu, Sedat Akdeniz, Isa An, Derya Uçmak
Rok vydání:	2018
Předmět:	0301 basic medicine Prurigo pigmentosa Adolescent Inflammation Dermatology Pharmacology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Hyperpigmentation medicine Antiinflammatory Effect Colchicine Effective treatment Humans Therapy systemic Skin business.industry Inflammatory skin disease medicine.disease Tubulin Modulators Neutrophil chemotaxis 030104 developmental biology Treatment Outcome chemistry Pediatrics Perinatology and Child Health Female Prurigo medicine.symptom business
Zdroj:	Pediatric dermatology. 35(3)
ISSN:	1525-1470
Popis:	Prurigo pigmentosa (PP) is a rare inflammatory skin disease. Neutrophil-mediated inflammation is considered to be responsible for the etiopathogenesis of PP. We consider that colchicine may be an effective agent in the treatment of PP since it exerts an antiinflammatory effect by inhibiting neutrophil chemotaxis. Further studies are required to verify whether colchicine is an effective treatment option for PP.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4295e8ad09638ddf2cb06cf533b0ce8 https://pubmed.ncbi.nlm.nih.gov/29644750 Zobrazit plný text záznamu Plný text