The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk
| Autor: | Inger Björck, Ulrika Gunnerud, Elin Östman, Jens J. Holst |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Whey protein medicine.medical_treatment Medicine (miscellaneous) Pilot Projects chemistry.chemical_compound fluids and secretions Glucagon-Like Peptide 1 Casein Lactose Amino Acids Intestinal Mucosa lcsh:RC620-627 Meal GIP Nutrition and Dietetics Cross-Over Studies digestive oral and skin physiology Human milk food and beverages Caseins Milk Proteins lcsh:Nutritional diseases. Deficiency diseases Glycemic index Postprandial Milk Female Bovine milk lcsh:Nutrition. Foods and food supply Adult medicine.medical_specialty lcsh:TX341-641 Incretins Young Adult Internal medicine Hyperinsulinism medicine Animals Humans Pancreas Glycemic Breakfast Milk Human business.industry Insulin Research Endocrinology Whey Proteins chemistry Glycemic Index Hyperglycemia Cattle business GLP-1 |
| Zdroj: | Nutrition Journal Nutrition Journal, Vol 11, Iss 1, p 83 (2012) |
| ISSN: | 1475-2891 |
| Popis: | Background Dairy proteins, in particular the whey fraction, exert insulinogenic properties and facilitate glycemic regulation through a mechanism involving elevation of certain plasma amino acids, and stimulation of incretins. Human milk is rich in whey protein and has not been investigated in this respect. Method Nine healthy volunteers were served test meals consisting of human milk, bovine milk, reconstituted bovine whey- or casein protein in random order. All test meals contributed with 25g intrinsic or added lactose, and a white wheat bread (WWB) meal was used as reference, providing 25g starch. Post-prandial levels in plasma of glucose, insulin, incretins and amino acids were investigated at time intervals for up to 2 h. Results All test meals elicited lower postprandial blood glucose responses, expressed as iAUC 0–120 min compared with the WWB (P Conclusion This study shows that the glycemic response was significantly lower following all milk/milk protein based test meals, in comparison with WWB. The effect appears to originate from the protein fraction and early phase plasma amino acids and incretins were involved in the insulin secretion. Despite its lower protein content, the human milk was a potent GLP-1 secretagogue and showed insulinogenic properties similar to that seen with reconstituted bovine whey-protein, possibly due to the comparatively high proportion of whey in human milk. |
| Databáze: | OpenAIRE |
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