Patient quality of life and pain improve after autologous islet transplantation (AIT) for treatment of chronic pancreatitis: 53 patient series at the University of Arizona
| Autor: | Angelika C. Gruessner, M. Delbridge, B. Grigsby, George Ivanov Georgiev, M. Beltran del Rio, Rainer W.G. Gruessner, H. Rilo, Renee Cercone, Mukesh Tiwari |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty SF-36 Visual analogue scale Endocrinology Diabetes and Metabolism medicine.medical_treatment Population Islets of Langerhans Transplantation Transplantation Autologous Pancreatectomy Quality of life Pancreatitis Chronic Surveys and Questionnaires medicine Humans education Pain Measurement education.field_of_study Pain Postoperative Hepatology business.industry Gastroenterology Middle Aged medicine.disease Surgery Abdominal Pain Pain Intractable Transplantation Treatment Outcome Preoperative Period Quality of Life Pancreatitis Intractable pain Female business Follow-Up Studies |
| Zdroj: | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 15(1) |
| ISSN: | 1424-3911 |
| Popis: | Background/objectives Pancreatectomy with autologous islet transplantation has slowly been proving to be an effective way of treating chronic pancreatitis while lessening the effects of the concomitant surgical diabetes of pancreatectomy alone. Assessing patient quality of life and pain after the procedure is particularly important as intractable pain is the main complaint for which patients undergo total pancreatectomy. Methods We used the Rand SF-36 and McGill pain questionnaires, and Visual Analogue Scale to assess patients preoperatively for quality of life and pain resulting from life with chronic pancreatitis. After undergoing total pancreatectomy with autologous islet transplantation (TPAIT), patients were followed with surveys administered at 1 month, 6 months, and 1 year to evaluate changes in their quality of life and pain experienced. Results Significant improvement was reported in all components of every questionnaire within a year after surgery. Furthermore, patient reported mean scores on quality of life were found to fall within the range of the general population. Conclusions From our experience with 53 patients at the University of Arizona, after pancreatectomy with autologous islet transplantation patients reported a higher quality of life when compared to preoperative values, as well as reduced levels of pain. |
| Databáze: | OpenAIRE |
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