Pulmonologist-Performed Per-Esophageal Needle Aspiration of Parenchymal Lung Lesions Using an EBUS Bronchoscope

Autor: Daniel P Steinfort, Louis Irving, Michael Farmer, Barton R Jennings
Rok vydání: 2017
Předmět:
Pulmonary and Respiratory Medicine
Endoscopic ultrasound
medicine.medical_specialty
Lung Neoplasms
Diagnostic accuracy
Adenocarcinoma
Sensitivity and Specificity
Cohort Studies
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Bronchoscopy
Carcinoma
Non-Small-Cell Lung

medicine
Humans
Prospective Studies
Endobronchial ultrasound
skin and connective tissue diseases
Endoscopic Ultrasound-Guided Fine Needle Aspiration
neoplasms
Pulmonologists
Lung
medicine.diagnostic_test
business.industry
Pneumothorax
Pulmonologist
medicine.disease
Small Cell Lung Carcinoma
digestive system diseases
body regions
Bronchoscopes
surgical procedures
operative

medicine.anatomical_structure
030228 respiratory system
030220 oncology & carcinogenesis
Carcinoma
Squamous Cell

Esophagoscopy
Radiology
Tomography
X-Ray Computed

business
Zdroj: Journal of Bronchology & Interventional Pulmonology. 24:117-124
ISSN: 1944-6586
Popis: Transesophageal introduction of the endobronchial ultrasound (EBUS) videobronchoscope allows pulmonologists to perform endoscopic ultrasound fine-needle aspiration (EUS-B-FNA) of mediastinal lesions. Safety, diagnostic accuracy, and feasibility of EUS-B-FNA in evaluation of pulmonary parenchymal lesions are not established.All patients undergoing pulmonologist-performed EUS-B-FNA of parenchymal lung lesions at 2 tertiary centers were included in this prospective observational cohort study.EUS-B-FNA sampling of parenchymal lesions was performed in 27 patients. Mean (±SD) lesion size was 36±16 mm. Seven lesions were ≤18 mm. Pneumothorax occurred in 1 patient (3.7%, 95% confidence interval, 0.001%-19%). Ten target lesions (36%) were in locations inaccessible to bronchoscopic sampling via the airways, and 9 lesions were inaccessible to EBUS-guided transbronchial needle aspiration and in locations associated with low diagnostic yield from radial EBUS. EUS-B-FNA was diagnostic in 26 patients (96%), and sensitivity of EUS-B-FNA was 100% (95% confidence interval, 87%-100%) for both lung cancer (n=21) and for pulmonary metastatic lesions (n=5).Pulmonologist-performed EUS-B-FNA is safe and accurate in the evaluation parenchymal lung lesions. Diagnostic accuracy is high. EUS-B-FNA may achieve access to sites not amenable to other forms of bronchoscopic sampling, or increase diagnostic accuracy in patients where anatomic position predicts a low diagnostic yield.
Databáze: OpenAIRE