Synthesis and general properties of silated-hydroxypropyl methylcellulose in prospect of biomedical use

Autor: Xavier Bourges, Pierre Weiss, Guy Daculsi, Gilbert Legeay
Přispěvatelé: Laboratoire d'ingénierie osteo-articulaire et dentaire (LIOAD), Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM), Département Matériaux (DMCTT), Centre de Transfert de Technologie du Mans, Weiss, Pierre
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Calcium Phosphates
Ceramics
MESH: Hydrogen-Ion Concentration
MESH: Materials Testing
MESH: Sterilization
MESH: Powders
chemistry.chemical_compound
Colloid and Surface Chemistry
Hypromellose Derivatives
MESH: Methylcellulose
Materials Testing
Spectroscopy
Fourier Transform Infrared
MESH: Sodium
MESH: Animals
MESH: Kinetics
Chemistry
Viscosity
Surfaces and Interfaces
Hydrogen-Ion Concentration
Silanes
MESH: Calcium Phosphates
Silanol
Powders
Rheology
MESH: Hardness
MESH: Gels
Kinetics
MESH: Viscosity
Ether
MESH: Bone Substitutes
Methylcellulose
MESH: Spectroscopy
Fourier Transform Infrared
Catalysis
MESH: Ceramics
Hardness
MESH: Rheology
Polymer chemistry
Animals
MESH: Silanes
Physical and Theoretical Chemistry
Cellulose
[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials
Sodium
Sterilization
Sterilization (microbiology)
Silane
[SDV.IB.BIO] Life Sciences [q-bio]/Bioengineering/Biomaterials
Chemical engineering
Bone Substitutes
Gels
Zdroj: Advances in Colloid and Interface Science
Advances in Colloid and Interface Science, Elsevier, 2002, 99 (3), pp.215-28
ISSN: 0001-8686
Popis: International audience; Synthesis of grafting silane on a hydro soluble cellulose ether (HPMC) was described. In alkaline medium, this derivate is under gel form. With a decrease of the pH, a self-hardening occurs due to the silanol condensation. For potential biomedical use, we described the silated-HPMC synthesis, the gel behavior after steam sterilization and the parameters of the silanol condensation i.e. pH, silane percentage and temperature. Minimum kinetic of the condensation was observed for pH between 5.5 and 6.5. So temperature catalyzed the reaction and the self-hardening speed was increased by silane percentage.
Databáze: OpenAIRE
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