The sorption of benzocaine from aqueous solution by nylon 6 powder
| Autor: | B. J. Meakin, N. E. Richardson |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Benzocaine
Inorganic chemistry Pharmaceutical Science Electrolyte Potassium Chloride chemistry.chemical_compound medicine Pharmacology chemistry.chemical_classification Aqueous solution Chemistry Hydrogen bond Temperature Sorption Polymer Hydrogen-Ion Concentration Molecular Weight Kinetics Nylons Nylon 6 Solubility Ionic strength Adsorption Powders medicine.drug |
| Zdroj: | Journal of Pharmacy and Pharmacology. 26:166-174 |
| ISSN: | 2042-7158 0022-3573 |
| DOI: | 10.1111/j.2042-7158.1974.tb09249.x |
| Popis: | The sorption of benzocaine by nylon 6 powder from aqueous solution has been examined under varying environmental conditions. The extent of sorption increases with increase in electrolyte concentration, and with pH up to about pH 4. Increasing temperature reduces the amount of drug sorbed. In all cases, the sorption isotherms were linear over the concentration ranges studied, and can be described by a simple distribution law which allows the effects of ionic strength and pH to be predicted. The interaction is believed to involve hydrogen bond formation between benzocaine and the amide groups of the nylon after penetration of the polymer matrix by the drug. |
| Databáze: | OpenAIRE |
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