The Italian Twin Registry: An Update at 18 Years From Its Inception
| Autor: | Cristina D'Ippolito, Maurizio Ferri, Emanuela Medda, Sonia Brescianini, Maria Antonietta Stazi, Sabrina Alviti, Miriam Salemi, Corrado Fagnani, Lorenza Nisticò, Virgilia Toccaceli, Antonio Arnofi |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Behavioral phenotypes Adolescent International studies Population 030204 cardiovascular system & hematology Dizygotic twins 03 medical and health sciences Young Adult 0302 clinical medicine Surveys and Questionnaires Diseases in Twins Twins Dizygotic Medicine Humans Registries education Child Genetics (clinical) Aged Retrospective Studies International research Aged 80 and over education.field_of_study business.industry Infant Newborn Obstetrics and Gynecology Infant Twins Monozygotic Middle Aged Prognosis Mental health Twin study Biobank Italy Child Preschool Pediatrics Perinatology and Child Health Quality of Life Female business 030217 neurology & neurosurgery Demography Follow-Up Studies |
| Zdroj: | Twin research and human genetics : the official journal of the International Society for Twin Studies. 22(6) |
| ISSN: | 1832-4274 |
| Popis: | The Italian Twin Registry (ITR), established in 2001, is a population-based registry of voluntary twins. To date, it consists of approximately 29,000 twins who gave their consent to participate in the studies proposed by the ITR research group. The database comprises 11,500 monozygotic and 16,700 dizygotic twins resident throughout the country and belonging to a wide age range (from 0 to 95 years, mean 36.8 years). This article provides an overview of the recruitment strategies along with the major phenotypes investigated during an 18 years’ research period. Over the years, several self-reported questionnaire data were collected, together with saliva/blood samples and measurements taken during in-person interviews or outpatient clinical examinations. Mental and behavioral phenotypes as well as atherosclerotic traits were studied in depth across different age groups. A birth cohort of twins was established and followed up. Novel research hypotheses are also being tested in ongoing projects. The ITR is involved in international studies in collaboration with other twin registries and represents a valuable resource for national and international research initiatives regarding a broad spectrum of health-related characteristics. |
| Databáze: | OpenAIRE |
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