COMPARISON OF IMMUNOARRAYS FOR SYPHILIS DIAGNOSTICS PRODUCED BY CO-POLYMERIZATION IMMOBILIZATION AND NON-CONTACT PRINTING TECHNIQUES
| Autor: | M. V. Shpilevaya, A. V. Runina, M A Filippova, Alexey A. Kubanov |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Immunoassay
0303 health sciences Computer science Protein immobilization T pallidum 030302 biochemistry & molecular biology Biochemistry (medical) Context (language use) General Medicine medicine.disease Sensitivity and Specificity Polymerization Syphilis Serodiagnosis 03 medical and health sciences Medical Laboratory Technology 0302 clinical medicine 030220 oncology & carcinogenesis Printing Three-Dimensional medicine Humans Syphilis Treponema pallidum Biomedical engineering |
| Zdroj: | Russian Clinical Laboratory Diagnostics. 65:16-23 |
| ISSN: | 0869-2084 |
| Popis: | The aim of the study was to investigate the characteristics of immunoarrays (microarrays) produced by co-polymerization immobilization and non-contact printing techniques for enhancing the capacities of syphilis diagnostics. In diagnostic context immunoarrays of both protein immobilization techniques have shown high sensitivity and specificity together with potency to differentiate syphilis stages in serologic assays. The article discloses the advantages and limitations of non-contact printing techniques as well as the results and problems revealed in the study. Solution of these problems in future may provide the development of new serodiagnostic tools with higher accuracy of the results. |
| Databáze: | OpenAIRE |
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