38P Overall survival in non-smokers and quitters compared to smokers who develop lung cancer: Case–control data from routine clinical practice

Autor: Birgit Schwenk, Matthias Leschke, R. Eckert, F. Liewald, M. Geissler, Martin Faehling
Rok vydání: 2016
Předmět:
Zdroj: Journal of Thoracic Oncology. 11:S71
ISSN: 1556-0864
DOI: 10.1016/s1556-0864(16)30152-6
Popis: recently implicated as a causative agent in lung cancer especially in women. We conducted a case control study to find out the role of Domestic Cooking Fuel as a risk factor for Lung Cancer in Indian women. Methods: In the case control study 67 women with proven lung cancer were recruited. Forty-six females having a non-malignant respiratory disease constituted the control group. The patients and controls were asked about the exposure in various cooking fuels using a questionnaire. Results: There were 50(74.6%) non-smokers and 17(25.4%) smokers among the female cancer cases (p = 0.016). Adenocarcinoma was the commonest histological type of malignancy (n = 26, 38.8%) in the whole group and was the predominant form in the non-smoking females. Tobacco smoking was the most important risk factor for lung cancer with OR of 4.87 (95% CI 1.34–17.76). Among non-smokers out of all the cooking fuels the risk of development of lung cancer was highest for biomass fuel exposure with an odds ratio of 5.33 (95% CI 1.7–16.7). Use of mixed fuels was associated with a lesser risk (OR=3.04, 95% CI 1.1–8.38). Conclusions: This study indicated that domestic cooking fuel exposure is an important risk factor in the causation of lung cancer among women in addition of exposure to tobacco smoke. Legal entity responsible for the study: PSM Dental College and Hospital Funding: PSM Dental College and Hospital Disclosure: All authors have declared no conflicts of interest.
Databáze: OpenAIRE