Orally administered resveratrol enhances the therapeutic effect of autologous transplanted adipose-derived stem cells on rats with diabetic hepatopathy

Autor:	Tung Sheng Chen, Peiying Pai, Y. M. Lin, Vijaya Padmaviswanadha, C. H. Lai, Chih Yang Huang, Ray-Jade Chen, M. C. Chen, C. Y. Shen, C. K. Yang
Rok vydání:	2019
Předmět:	Male 0301 basic medicine Histology endocrine system diseases medicine.medical_treatment Administration Oral Adipose tissue Resveratrol Pharmacology Thiobarbituric Acid Reactive Substances Antioxidants Diabetes Mellitus Experimental 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Diabetes mellitus Animals Medicine Rats Wistar 030102 biochemistry & molecular biology business.industry Liver Diseases Stem Cells Therapeutic effect General Medicine Stem-cell therapy medicine.disease Rats Transplantation Medical Laboratory Technology Adipose Tissue Liver chemistry 030220 oncology & carcinogenesis business Stem Cell Transplantation
Zdroj:	Biotechnic & Histochemistry. 95:37-45
ISSN:	1473-7760 1052-0295
DOI:	10.1080/10520295.2019.1631481
Popis:	Stem cell therapy is a promising treatment for hepatopathy due to diabetes mellitus (DM); oral resveratrol treatment exhibits protective effects. We investigated whether protective effects could be produced in liver of diabetic rats receiving autologous adipose-derived stem cell transplantation (ADSC) plus oral resveratrol administration. Male rats were divided into four groups: sham group; streptozotocin induced DM group; DM + ADSC group, in which DM rats were treated with 10
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f530b7737e8574d70ee5976d658ecb https://doi.org/10.1080/10520295.2019.1631481 Zobrazit plný text záznamu