Photorefractive intrastromal corneal crosslinking for the treatment of myopic refractive errors: Six-month interim findings
| Autor: | Matthias Elling, H. Burkhard Dick, Inga Kersten-Gomez |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Refractive error Distance visual acuity Visual acuity genetic structures Riboflavin Visual Acuity Spherical equivalent Refraction Ocular Cornea Myopic astigmatism 03 medical and health sciences 0302 clinical medicine Ophthalmology Myopia Humans Medicine business.industry Astigmatism Photorefractive effect Refractive Errors medicine.disease Refraction eye diseases Sensory Systems Cross-Linking Reagents 030104 developmental biology medicine.anatomical_structure 030221 ophthalmology & optometry Optometry Surgery sense organs medicine.symptom business |
| Zdroj: | Journal of Cataract and Refractive Surgery. 43:789-795 |
| ISSN: | 0886-3350 |
| Popis: | To evaluate the safety and efficacy of photorefractive intrastromal corneal crosslinking (CXL) in low myopia.Ruhr University Eye Hospital, Bochum, Germany.Prospective case series.Healthy eyes with myopia or myopic astigmatism had photorefractive intrastromal CXL using the Mosaic system to apply ultraviolet-A (UVA) 365 nm (30 mW/cmTwenty-six eyes of 14 patients with a mean age of 30.8 years ± 9.3 (SD) were included. There were statistically significant improvements in UDVA 1, 3, and 6 months postoperatively (all P .001). A significant improvement in CDVA was observed (P = .02). Improvements in the mean manifest sphere and MRSE versus baseline were noted at all visits (P .001), with a mean change of 0.99 ± 0.47 diopter (D) and 0.97 ± 0.48 D, respectively, by 6 months postoperatively. Significant reductions in corneal curvature versus baseline occurred at all follow-up visits (all P .05). At 1 month, there were no significant changes in the endothelial cell density (P = .282) or number of cells (P = .069). No safety issues or complications were reported.The findings show that patterned CXL using a custom CXL system is safe and effective for reducing myopic refractive error. |
| Databáze: | OpenAIRE |
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