Arterial Wall Stiffness and the Risk of Atherosclerosis in Egyptian Patients with Overt and Subclinical Hypothyroidism
| Autor: | Shrook Mousa, Alaa H. Abdel-Hamid, Aasem Saif, Hamed Ghorab, Afaf Hemeda |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Adolescent endocrine system diseases Endocrinology Diabetes and Metabolism Group ii 030209 endocrinology & metabolism Pulse Wave Analysis Carotid Intima-Media Thickness Young Adult 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Endocrinology Hypothyroidism Risk Factors Internal medicine medicine Humans Ankle Brachial Index Euthyroid Arterial wall cardiovascular diseases 030212 general & internal medicine Young adult Pulse wave velocity Subclinical infection business.industry General Medicine Middle Aged Atherosclerosis Blood pressure cardiovascular system Cardiology Egypt Female business hormones hormone substitutes and hormone antagonists Lipoprotein |
| Zdroj: | Endocrine Practice. 26:161-166 |
| ISSN: | 1530-891X |
| DOI: | 10.4158/ep-2019-0322 |
| Popis: | Objective: Hypothyroidism is associated with an increased risk of atherosclerosis. Pulse wave velocity (PWV) is an index of arterial wall stiffness widely used for noninvasive assessment of early atherosclerosis. We assessed PWV in Egyptian patients with hypothyroidism. Methods: The study included 100 Egyptian females aged 18 to 55 years. They were classified into three groups: group I, 40 women with overt hypothyroidism; group II, 40 women with subclinical hypothyroidism; and group III, 20 euthyroid women as a control group. The three groups were age matched. Doppler ultrasonography was used to calculate the heart-femoral PWV. Results: PWV was significantly higher in women with overt and subclinical hypothyroidism as compared with the control group (9.55 ± 1.81 m/s and 9.30 ± 1.28 m/s, respectively vs. 7.82 ± 2.14 m/s; P |
| Databáze: | OpenAIRE |
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