Correspondence re: Cecchin et al., Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. Clin Cancer Res 2005;11:6901-7
Autor: | Darren Lim Wan Teck, Srinivas Rao Jada, Balram Chowbay |
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Rok vydání: | 2006 |
Předmět: |
Gene isoform
Cancer Research Colorectal cancer Irinotecan Peripheral blood mononuclear cell Gene Expression Regulation Enzymologic Carboxylesterase Predictive Value of Tests Antineoplastic Combined Chemotherapy Protocols medicine Biomarkers Tumor Humans RNA Messenger Predictive marker business.industry Cancer medicine.disease Gene Expression Regulation Neoplastic Isoenzymes Oncology Cohort Immunology Cancer research Leukocytes Mononuclear Camptothecin business Colorectal Neoplasms medicine.drug |
Zdroj: | Clinical cancer research : an official journal of the American Association for Cancer Research. 12(6) |
ISSN: | 1078-0432 |
Popis: | To the Editor: Cecchin and colleagues reported their interesting findings on the use of carboxylesterase 2 (CES2) mRNA expression in peripheral blood mononuclear cells (PBMC) as a predictive marker of irinotecan to SN38 activation in a cohort of Italian colorectal cancer patients receiving a twice |
Databáze: | OpenAIRE |
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