Plasma lactate concentration as a prognostic biomarker in dogs with gastric dilation and volvulus
| Autor: | Dez Hughes, Erin Mooney, Cameron Raw |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Lactate concentration
medicine.medical_specialty Resuscitation Gastric Dilation business.industry Exploratory laparotomy medicine.medical_treatment Stomach Volvulus Gastric Dilatation Gastric necrosis medicine.disease Gastroenterology Volvulus Surgery Dogs Internal medicine Medicine Animals Prognostic biomarker Hyperlactatemia Dog Diseases Lactic Acid Small Animals business Biomarkers |
| Zdroj: | Topics in companion animal medicine. 29(3) |
| ISSN: | 1946-9837 |
| Popis: | Initial and serial plasma lactate concentrations can be used to guide decision making in individual dogs with GDV but care is necessary in phrasing conversations with owners. Published data suggests that survival is more likely and the chance of complications less in dogs with an initial plasma lactate of4 mmol/L. An initial lactate6 mmol/L makes gastric necrosis and greater expense more likely. However, because of the overlap between groups and the good overall survival rates, exploratory laparotomy should always be recommended irrespective of the plasma lactate concentration. Falls in plasma lactate of greater than ~40% after fluid resuscitation are likely to indicate better survival. If the initial plasma lactate concentration is moderately to severely increased (5-10 mmol/L) and a sustained increase in plasma lactate occurs after fluid resuscitation, the cause should be aggressively pursued. Many dogs with persistent hyperlactatemia over 24-48 hours do not survive. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect