Effect of different salivary glucose concentrations on dual-species biofilms of Candida albicans and Streptococcus mutans
| Autor: | Yuri Wanderley Cavalcanti, Leopoldina de Fátima Dantas de Almeida, Maria Heloísa de Souza Borges, Arella Cristina Muniz Brito, Isis Morais Bezerra |
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| Rok vydání: | 2021 |
| Předmět: |
Saliva
biology Chemistry fungi Biofilm food and beverages biochemical phenomena metabolism and nutrition Aquatic Science biology.organism_classification medicine.disease Applied Microbiology and Biotechnology Streptococcus mutans Microbiology Salivary glucose Diabetes mellitus medicine Candida albicans Biofilm growth Water Science and Technology Dual species biofilms |
| Zdroj: | Biofouling. 37:615-625 |
| ISSN: | 1029-2454 0892-7014 |
| DOI: | 10.1080/08927014.2021.1946519 |
| Popis: | Diabetes mellitus is one of the most prevalent diseases worldwide. The glucose levels found in the blood of diabetic patients can be reflected in the saliva, which can favor biofilm growth and predispose denture wearers to oral candidiasis. This study aimed to evaluate the effect of different salivary glucose concentrations on dual-species biofilms of Candida albicans and Streptococcus mutans. A 96-h biofilm was developed on acrylic resin specimens exposed to ‘feast’ (10% sucrose) and ‘famine’ periods. Biofilms were constantly exposed to salivary glucose concentrations equivalent to 0, 20, 60 and 100 mM. Higher salivary glucose concentrations resulted in increased counts of C. albicans and a higher quantity of insoluble extracellular polysaccharides. All biofilms presented high phospholipase activity. The biofilms were characterized by the predominance of yeast cells and microcolonies in all the groups analyzed with co-localization of both species. Higher salivary glucose concentrations formed more robust and potentially virulent biofilms. |
| Databáze: | OpenAIRE |
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