A new approach based on CXCR4-targeted combination liposomes for the treatment of liver fibrosis

Autor:	Aftab Ullah, Gang Chen, Zhang Yibang, Abid Hussain, Muhammad Shafiq, Faisal Raza, Daojun Liu, Kaikai Wang, Jin Cao, Xueyong Qi
Rok vydání:	2022
Předmět:	Liver Cirrhosis Receptors CXCR4 Biomedical Engineering Fibrosis Collagen Type I digestive system diseases Mice Liver Transforming Growth Factor beta Liposomes Animals Tissue Distribution General Materials Science Molecular Targeted Therapy
Zdroj:	Biomaterials Science. 10:2650-2664
ISSN:	2047-4849 2047-4830
DOI:	10.1039/d2bm00242f
Popis:	Liver fibrosis results from excessive extracellular matrix accumulation due to injury and leads to cirrhosis, cancer, and death. Herein, we propose a chemokine receptor 4 (CXCR4)-targeted combination (CTC) liposomal therapy to treat carbon tetrachloride (CCl
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e0762e0abe5a1cf461f677add88c79 https://doi.org/10.1039/d2bm00242f Zobrazit plný text záznamu