Retrospective And Prospective Studies Of Hemorrhagic Fever With Renal Syndrome In Rural China

Autor: Susan P. Fisher-Hoch, Joseph B. McCormick, Suyu L. Ruo, Yong L. Li, Zheng Tong, Qou R. Ma, Zhi Y. Xu, Zhao L. Liu, Yi W. Tang, Ke L. Ye
Rok vydání: 1994
Předmět:
Zdroj: Journal of Infectious Diseases. 170:527-534
ISSN: 1537-6613
0022-1899
Popis: Residents of two villages in Zhejiang Province, China, were interviewed and serum samples were collected to assess prevalence of hantavirus infection. Antibody prevalence was 12% (219/1811), with a ratio of illness to infection of 1.0:5.4. Seroprevalence increased with age, but no association was found with sex. There was also no evidence of vertical transmission. One year later, 2.3% (30/1325) of seronegative subjects had seroconverted including 2 who had hemorrhagic fever with renal syndrome. Peak incidence of infection occurred in those 15-39 years old. Hantaan was the dominant serotype; Seoul serotype was less common (5:1). Host reservoirs were Apodemus agrarius in agricultural fields and Rattus norvegicus in houses. Risk factors for infection were traces of rat-contaminated food, travel to other areas for farm work, direct rodent contact, camping in grain fields, living in a house on the periphery of a village, stacking straw stacks outside houses, and keeping cats. All may provide exposure to infectious rodent reservoirs.
Databáze: OpenAIRE