Clinical manifestations of mannan-binding lectin deficiency
| Autor: | Jens Chr. Jensenius, Steffen Thiel, Pernille Dorthea Frederiksen |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Neutropenia
Immunology Population Autoimmunity chemical and pharmacologic phenomena Infections medicine.disease_cause Mannose-Binding Lectin Article Autoimmune Diseases Microbiology Mice Immune system Immunity Sepsis medicine Animals Humans Vascular Diseases education Molecular Biology Mannan-binding lectin Mice Knockout Innate immunity Mannose-binding lectin education.field_of_study Innate immune system biology Lectin Blood Proteins bacterial infections and mycoses MBL deficiency medicine.disease Immunity Innate Systemic Inflammatory Response Syndrome biology.protein Infection |
| Zdroj: | Molecular Immunology Aarhus University Thiel, S, Frederiksen, P D & Jensenius, J C 2005, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 . Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 . Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Molecular Immunology, vol. 43, no. 1-2, pp. 86-96 . https://doi.org/10.1016/j.molimm.2005.06.018 |
| ISSN: | 0161-5890 |
| Popis: | Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far. |
| Databáze: | OpenAIRE |
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