Effect of minimally invasive autopsy and ethnic background on acceptance of clinical postmortem investigation in adults

Autor: Jan A. Kors, M. G. Myriam Hunink, Annick C. Weustink, Ivo M. Wagensveld, J. W. Oosterhuis, Britt M. Blokker
Přispěvatelé: Pathology, Radiology & Nuclear Medicine, Medical Informatics, Epidemiology
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Medical Doctors
Biopsy
Health Care Providers
Autopsy
030204 cardiovascular system & hematology
Single Center
Diagnostic Radiology
0302 clinical medicine
Cause of Death
Ethnicity
Medicine and Health Sciences
Ethnicities
Prospective Studies
Medical Personnel
Prospective cohort study
Cause of death
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
Magnetic Resonance Imaging
Hospitals
Professions
030220 oncology & carcinogenesis
Medicine
Female
Radiology
Research Article
Adult
Image-Guided Biopsy
medicine.medical_specialty
Imaging Techniques
Science
Subgroup analysis
Surgical and Invasive Medical Procedures
Minimally Invasive Surgery
Research and Analysis Methods
03 medical and health sciences
Diagnostic Medicine
medicine
Humans
business.industry
Conventional autopsy
Magnetic resonance imaging
Health Care
Health Care Facilities
People and Places
Population Groupings
business
Tomography
X-Ray Computed
Zdroj: PLoS ONE, Vol 15, Iss 5, p e0232944 (2020)
PLoS ONE
PLoS One (print), 15(5):e0232944. Public Library of Science
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0232944
Popis: ObjectivesAutopsy rates worldwide have dropped significantly over the last five decades. Imaging based autopsies are increasingly used as alternatives to conventional autopsy (CA). The aim of this study was to investigate the effect of the introduction of minimally invasive autopsy, consisting of CT, MRI and tissue biopsies on the overall autopsy rate (of CA and minimally invasive autopsy) and the autopsy rate among different ethnicities.MethodsWe performed a prospective single center before-after study. The intervention was the introduction of minimally invasive autopsy as an alternative to CA. Minimally invasive autopsy consisted of MRI, CT, and CT-guided tissue biopsies. Autopsy rates over time and the effect of introducing minimally invasive autopsy were analyzed with a linear regression model. We performed a subgroup analysis comparing the autopsy rates of two groups: a group of western-European ethnicity versus a group of other ethnicities.ResultsAutopsy rates declined from 14.0% in 2010 to 8.3% in 2019. The linear regression model showed a significant effect of both time and availability of minimally invasive autopsy on the overall autopsy rate. The predicted autopsy rate in the model started at 15.1% in 2010 and dropped approximately 0.1% per month (β = -0.001, p < 0.001). Availability of minimally invasive autopsy increased the overall autopsy rate by 2.4% (β = 0.024, p < 0.001). The overall autopsy rate of people with an ethnic background other than western-European was significantly higher in years when minimally invasive autopsy was available compared to when it was not (22/176 = 12.5% vs. 81/1014 (8.0%), p = 0.049).ConclusionsThe introduction of the minimally invasive autopsy had a small, but significant effect on the overall autopsy rate. Furthermore, the minimally invasive autopsy appears to be more acceptable than CA among people with an ethnicity other than western-European.
Databáze: OpenAIRE
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