Effect of Electroconvulsive Therapy on Cognitive Functions of Rats with Depression-Like Disorders Induced by Ultrasound Exposure
| Autor: | A. N. Inozemtsev, Vladimir P. Chekhonin, A. V. Gorlova, Anna Morozova, D. A. Pavlov, E. A. Zubkov, V. M. Ushakova |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Ultrasound exposure Audiology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Cognition 0302 clinical medicine Electroconvulsive therapy Memory Transient amnesia medicine Animals Electroconvulsive Therapy Depression (differential diagnoses) Depression business.industry Ultrasound General Medicine Rats 030227 psychiatry Behavioral test Ultrasonic Waves Anesthesia business 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 163:599-601 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-017-3857-0 |
| Popis: | We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy was demonstrated that manifested in amelioration of memory disturbances in depression-like disorders in these behavioral tests. The results of this study do not support the idea about side effects of electroconvulsive therapy, in particular, development of transient amnesia, and are a prerequisite for a more thorough study of internal mechanisms of the effect of the therapy on cognitive sphere. |
| Databáze: | OpenAIRE |
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