The Alterations in Peripheral Blood Components of Women with Abnormal Cervical Cytology

Autor: Egemen Akincioglu, Hande Esra Koca, Gamze Sinem Caglar, Mine Kiseli, Haldun Umudum, Zehra Edebal, Aslı Yarcı Gursoy, Emre Göksan Pabuçcu
Rok vydání: 2016
Předmět:
Zdroj: Gorm, Vol 22, Iss 1 (2016)
ISSN: 2602-4918
1300-4751
DOI: 10.21613/gorm.2016.109
Popis: OBJECTIVE: To investigate the peripheral blood components, neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratios (PLR) in cervical cytological abnormalities.STUDY DESIGN: We retrospectively analyzed 185 cases with abnormal and 303 cases with normal cervicovaginal smears (CVS) with blood count profile, from a total number of 9286 patients.RESULTS: Abnormal CVS results consisted of 137 (72%) ASC-US, 16 (8%) ASC-H, 19 (10%) L-SIL, 4 (2%) H-SIL and 9 (4%) AGUS. NLR and PLR of abnormal CVS group were higher than control group (p0.05).CONCLUSION: Neutrophilia is not observed in cervical preinvasive lesions whereas it is common in cervical cancer. In this study, absence of increased neutrophil counts and presence of lymphopenia in patients with abnormal cervical cytology, may indicate an early measure in cervical pathologies.
Databáze: OpenAIRE