The Alterations in Peripheral Blood Components of Women with Abnormal Cervical Cytology
Autor: | Egemen Akincioglu, Hande Esra Koca, Gamze Sinem Caglar, Mine Kiseli, Haldun Umudum, Zehra Edebal, Aslı Yarcı Gursoy, Emre Göksan Pabuçcu |
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Rok vydání: | 2016 |
Předmět: |
Pathology
medicine.medical_specialty business.industry Lymphocyte lcsh:R Blood count lcsh:Medicine lcsh:Gynecology and obstetrics Peripheral blood Neutrophilia medicine.anatomical_structure Abnormal cervical cytology medicine Cervicovaginal smear Atypical squamous cells of undetermined significance Neutrophil/lymphocyte ratio Platelet/lymphocyte ratio medicine.symptom business lcsh:RG1-991 |
Zdroj: | Gorm, Vol 22, Iss 1 (2016) |
ISSN: | 2602-4918 1300-4751 |
DOI: | 10.21613/gorm.2016.109 |
Popis: | OBJECTIVE: To investigate the peripheral blood components, neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratios (PLR) in cervical cytological abnormalities.STUDY DESIGN: We retrospectively analyzed 185 cases with abnormal and 303 cases with normal cervicovaginal smears (CVS) with blood count profile, from a total number of 9286 patients.RESULTS: Abnormal CVS results consisted of 137 (72%) ASC-US, 16 (8%) ASC-H, 19 (10%) L-SIL, 4 (2%) H-SIL and 9 (4%) AGUS. NLR and PLR of abnormal CVS group were higher than control group (p0.05).CONCLUSION: Neutrophilia is not observed in cervical preinvasive lesions whereas it is common in cervical cancer. In this study, absence of increased neutrophil counts and presence of lymphopenia in patients with abnormal cervical cytology, may indicate an early measure in cervical pathologies. |
Databáze: | OpenAIRE |
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