Infection related catheter complications in patients undergoing prone positioning for acute respiratory distress syndrome: an exposed/unexposed study
Autor: | Thibaut Belveyre, Christophe Goetz, Guillaume Louis, Audrey Jacquot, Nejla Aissa, Hélène Hochard, Bruno Levy, Emmanuel Novy, Antoine Kimmoun |
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Rok vydání: | 2020 |
Předmět: |
Colonization
Male ARDS medicine.medical_specialty Critical Care Prone positioning Infectious and parasitic diseases RC109-216 Severity of Illness Index Patient Positioning law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Severity of illness medicine Prone Position Humans 030212 general & internal medicine Aged Retrospective Studies Respiratory Distress Syndrome business.industry Research Incidence (epidemiology) Incidence 030208 emergency & critical care medicine Retrospective cohort study Middle Aged medicine.disease Intensive care unit Catheter Pneumonia Intensive Care Units Infectious Diseases SAPS II Catheter-Related Infections Catheter-related infection Female business |
Zdroj: | BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021) BMC Infectious Diseases |
ISSN: | 1471-2334 |
Popis: | Background Prone positioning (PP) is a standard of care for patients with moderate–severe acute respiratory distress syndrome (ARDS). While adverse events associated with PP are well-documented in the literature, research examining the effect of PP on the risk of infectious complications of intravascular catheters is lacking. Method All consecutive ARDS patients treated with PP were recruited retrospectively over a two-year period and formed the exposed group. Intensive care unit (ICU) patients during the same period without ARDS for whom PP was not conducted but who had an equivalent disease severity were matched 1:1 to the exposed group based on age, sex, centre, length of ICU stay and SAPS II (unexposed group). Infection-related catheter complications were defined by a composite criterion, including catheter tip colonization or intravascular catheter-related infection. Results A total of 101 exposed patients were included in the study. Most had direct ARDS (pneumonia). The median [Q1–Q3] PP session number was 2 [1–4]. These patients were matched with 101 unexposed patients. The mortality rates of the exposed and unexposed groups were 31 and 30%, respectively. The incidence of the composite criterion was 14.2/1000 in the exposed group compared with 8.2/1000 days in the control group (p = 0.09). Multivariate analysis identified PP as a factor related to catheter colonization or infection (p = 0.04). Conclusion Our data suggest that PP is associated with a higher risk of CVC infectious complications. |
Databáze: | OpenAIRE |
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