The antioxidant effect of natural polyphenolic complexes of grape wine in the rat retina under streptozotocin-induced diabetes mellitus
| Autor: | V. A. Zagoruyko, Wine „Magarach', Yalta, Crimea, Ukraine, Volodymyr I. Mizin, A. Ya. Yalaneckyy, A. R. Gnatush, Viktor R. Drel, Natalia Sybirna, V. G. Gerzhykova |
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| Rok vydání: | 2011 |
| Předmět: |
Antioxidant
QH301-705.5 Chemistry medicine.medical_treatment food and beverages Rat retina Pharmacology medicine.disease Streptozotocin Polyphenol Diabetes mellitus diabetes mellitus medicine oxidative stress Grape wine antioxidant protection polyphenolic complexes Biology (General) diabetes retinopathy medicine.drug |
| Zdroj: | Біологічні студії, Vol 5, Iss 2, Pp 61-72 (2011) |
| ISSN: | 2311-0783 1996-4536 |
| DOI: | 10.30970/sbi.0502.156 |
| Popis: | The protective effects of natural polyphenolic complexes of the grape wine on antioxidant system in retinae of rats under streptozotocin-induced diabetes mellitus are established. It was shown that proposed level of polyphenol speciment of the grape wine that was consumed did not change blood glucose concentrations in control and diabetic groups of animals. During the experiment the body weight of control group and diabetic groups of rats with consumption of studied speciment was significantly increased. The polyphenols completely or partially normalized the work of enzymatic antioxidant system (superoxide dismutase, catalase, glutathione reductase and glutathione peroxidase). It was shown that level of products of lipid peroxidation in the groups of rats with and without consumption of polyphenol speciment differed significantly. The presented results allow to suggest an important role of speciment of grape wine in preventing and treatment of diabetes retinopathy. |
| Databáze: | OpenAIRE |
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