Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
| Autor: | Virginia Martínez C, Ana María Gray H, María Elena Cabrera C, Marvila Intriago B, Camila Peña O |
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| Rok vydání: | 2012 |
| Předmět: |
Chemotherapy
Pathology medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment T cell General Medicine medicine.disease Cutaneous lymphoma Lymphoma medicine.anatomical_structure hemic and lymphatic diseases Biopsy medicine T-cell lymphoma Cytotoxic T cell Antineoplastic protocols Primary cutaneous CD8+ lymphoma Epidermis business CD8 |
| Zdroj: | Revista médica de Chile v.140 n.3 2012 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| DOI: | 10.4067/s0034-98872012000300014 |
| Popis: | Primary cutaneous aggressive epidermotropic cytotoxic CD8 positive T cell lymphoma, is an uncommon disease, with an aggressive clinical behavior. Differentiation with other types of cutaneous T-cell lymphoma (CTCL) that express a CD8+ cells, is based only on clinical grounds and in certain morphological characteristics, such as a marked epidermotropism with squamous cell necrosis. We report a 50-year-old male presenting with painless cutaneous lesions appearing in trunk, limbs, scalp and face, suggestive of cutaneous lymphoma. He was admitted to the hospital in bad conditions, with confluent papules and tumors, some of them ulcerated and with foul smelling honey-colored crusts, involving the complete body surface. Cutaneous biopsy demonstrated a CD8 positive epidermotropic cytotoxic T cell lymphoma. He was treated with chemotherapy with an excellent initial response, but cutaneous lesions reappeared after four cycles. He did not respond to rescue chemotherapy and died seven months after diagnosis. |
| Databáze: | OpenAIRE |
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